A doctor takes the temperature of a patient.

PCORI supports comparative clinical effectiveness research


The Patient-Centered Outcomes Research Institute (PCORI) was established in 2010 as an independent non-profit, non-governmental, special purpose corporation authorized by Congress.  PCORI’s Congressional mandate is to improve the quality and relevance of healthcare information to help patients and caregivers make informed decisions. Through contracts, PCORI funds comparative clinical effectiveness research (CER) while engaging patients and stakeholders in the research process.

Patients and stakeholders help PCORI  prioritize research questions, advising PCORI on what to fund.  Stakeholders are engaged in the review process and help PCORI share findings with the community at large.

Currently most of PCORI’s $200 million budget supports clinical trial research, with the remainder funding general and targeted areas such as cancer, cardiovascular health, mental/behavioral disorders, and rare diseases.

PCORI supports applications from for- and non-profit entities as well as from entities not located in the U.S. Individuals may not apply.  Applications to PCORI are typically for 3-5 year projects and applications are often invited through a Letter of Intent (LOI) process.  Because PCORI is commitment to working with all stakeholders PCORI staff will work with researchers who did not get funded to strengthen their proposals to better align with the target solicitation.

PCORI funds comparative clinical effectiveness research (CER), so all questions must be comparative in nature.

For more information on PCORI and the types of research they fund, visit their website, pcori.org.

Written by Tricia Callahah, Director of Proposal development, Office for the Advancement of Research & Scholarship, Miami University.

Doctor and patient photo by Amanda Mills, U.S. Centers of Disease Control & Prevention, public domain. Culture photo by Carlotte Raymond Photography for International AIDS Vaccine Initiative (IAVI) via Flickr, used under Creative Commons license.

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